Genencor Signs Licensing Agreement with Integrated Genomics for Microbial Genome Sequencing Technologies
Genencor International, Inc. (NASDAQ:GCOR) and Integrated Genomics
today announced the signing of a licensing agreement for three microbial genome
sequencing technologies. As part of the agreement, Genencor will have access to
Integrated Genomics’ Aspergillus niger genome sequence data, the ERGO™
bioinformatics suite and Genome Explorer™--a tool for analyzing regulatory
pathways. With these technologies, Genencor expects to continue to improve
efficiencies in fungal cell factories for commercial applications in both its
bioproducts and health care businesses.
“Over the years, we
have invested significantly in our functional genomics platform and we believe
that the A. niger genome sequence specifically will accelerate the pace of
enzyme discovery and production,” said Michael V. Arbige, senior vice president
of technology for Genencor. “The sequence data and the blueprint of metabolism
will lead us to design cell factories from a whole-system perspective for both
our bioproducts and health care projects. We believe that Integrated Genomics’
systems will continue to add value and advance our proprietary technology
position in this area.”
Recently, Integrated Genomics became
the first to determine the DNA sequence of A.niger, containing more than 34
million base pairs and estimated to encode 50 percent more genes than the yeast
Saccharomyces cerevisiae. The fungus, A.niger, is known for its efficient
conversion of simple molecules into complex biochemicals. Using its proprietary
bioinformatics suite, ERGO, Integrated Genomics has organized the genes and
functions of A. niger into metabolic networks. This “metabolic reconstruction”
provides a blueprint of the significant biochemical pathways required to produce
proteins and biochemicals in fermentations.
“Integrated
Genomics is pleased that Genencor finds our technology valuable,” said Michael
Fonstein, CEO of Integrated Genomics. “The sequence data and the metabolic
networks of A. niger are invaluable sources of information for the development
of a wide array of commercial applications. Any company with this information
should have a definite competitive edge.”
About
Integrated Genomics Integrated Genomics, Inc., based in
Chicago, Illinois, offers a systematic approach to solving genomic problems by
using pioneering methods of high-throughput sequencing, comparative analysis of
genomes, functional reconstruction, and metabolic modeling. Integrated Genomics'
analytical bioinformatics suite, ERGO™, is comprised of over 300 genomes making
it the largest biochemical database on the market. Integrated Genomics is
particularly strong in genome sequencing, annotation, and analytical chemistry.
Globally, the company is ranked in the top ten in genome analysis and functional
reconstruction with an aim to address problems in strain development, crop
protection, and drug discovery.
About
Genencor Genencor International is a diversified
biotechnology company that develops and delivers innovative products and
services into the health care, agriculture, industrial and consumer markets.
Using an integrated set of technology platforms, Genencor’s products deliver
innovative and sustainable solutions to many of the problems of everyday
life.
Genencor was established in 1982 as a joint venture
between Genentech Inc. and Corning Incorporated. Since its founding, Genencor
has grown to become a leading biotechnology company, with over $315 million in
year 2000 annual revenues, more than 250 biotechnology products in commerce, and
over 3,400 owned and licensed patents and applications. Genencor, with more than
1,500 employees worldwide, has principal offices in Palo Alto, California;
Rochester, New York; and Leiden, the Netherlands.
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information contained herein, the matters discussed in this press release may
contain forward-looking statements which involve risks and uncertainties,
including significant fluctuations in product performance depending on factors
such as a dependence on the efforts of third parties, new and uncertain
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